Cancer-associated osteoclast differentiation takes a good look in the miR(NA)ror.

نویسندگان

  • David L Waning
  • Khalid S Mohammad
  • Theresa A Guise
چکیده

Tumor-bone cell interactions are critical for the development of metastasis-related osteolytic bone destruction. In this issue of Cancer Cell, Ell and colleagues show how a discrete miRNA network regulates osteoclastogenesis during breast cancer bone metastasis. A signature of upregulated miRNAs may have diagnostic and therapeutic implications for bone metastases.

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عنوان ژورنال:
  • Cancer cell

دوره 24 4  شماره 

صفحات  -

تاریخ انتشار 2013